VISDB Viral Integration Site DataBase

VIS ID

TVIS10018538

Fusion event

HBV-POLR3A integration

Validated

No

Detection method

VirusFinder

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HBV

Reference genome

Start

1584

End

1866

Integrated sequence

ACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTA

Chromosome

chr10

Cytoband

q22.3

Reference genome

Start

End

79742077/77982319 (Hg38)

Location type

Intron4

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-16-5p ; hsa-mir-769-3p ; hsa-mir-10a-5p ; hsa-mir-92a-3p ; hsa-mir-5089-5p ; hsa-mir-6807-5p ; hsa-mir-331-5p ; hsa-mir-5589-5p ; hsa-mir-4731-5p ; hsa-mir-6506-5p ; hsa-mir-619-5p ; hsa-mir-556-5p ; hsa-mir-512-3p ; hsa-mir-4678 ; hsa-mir-449b-3p ; hsa-mir-6778-3p ; hsa-mir-150-5p ; hsa-mir-186-3p ; hsa-mir-520h ; hsa-mir-520g-3p ; hsa-mir-520e ; hsa-mir-520d-3p ; hsa-mir-520c-3p ; hsa-mir-520b ; hsa-mir-520a-3p ; hsa-mir-373-3p ; hsa-mir-372-3p ; hsa-mir-302e ; hsa-mir-302d-3p ; hsa-mir-302c-3p ; hsa-mir-302b-3p ; hsa-mir-302a-3p ; hsa-mir-93-5p ; hsa-mir-526b-3p ; hsa-mir-519d-3p ; hsa-mir-20b-5p ; hsa-mir-20a-5p ; hsa-mir-17-5p ; hsa-mir-106b-5p ; hsa-mir-106a-5p ; hsa-mir-640 ; hsa-mir-7107-5p ; hsa-mir-1234-3p ; hsa-mir-1281 ; hsa-mir-6777-3p ; hsa-mir-3934-5p ; hsa-mir-764 ; hsa-mir-125a-3p ; hsa-mir-4701-5p ; hsa-mir-4482-3p ; hsa-mir-7159-3p ; hsa-mir-4775 ; hsa-mir-138-2-3p ; hsa-mir-4735-5p ; hsa-mir-500b-3p ; hsa-mir-590-3p ; hsa-mir-1303 ; hsa-mir-5096 ; hsa-mir-6848-3p ; hsa-mir-6843-3p ; hsa-mir-3187-3p ; hsa-mir-4435 ; hsa-mir-588 ; hsa-mir-548s ; hsa-mir-519e-5p ; hsa-mir-515-5p ; hsa-mir-378a-5p ; hsa-mir-197-3p ; hsa-mir-193b-5p ; hsa-mir-6131 ; hsa-mir-4755-3p ; hsa-mir-3663-5p ; hsa-mir-3653-5p ; hsa-mir-5695 ; hsa-mir-519d-5p ; hsa-mir-4716-5p ; hsa-mir-4781-3p ; hsa-mir-483-5p ; hsa-mir-1273f ; hsa-mir-1289 ; hsa-mir-143-3p ; hsa-mir-3198 ; hsa-mir-4251 ; hsa-mir-4294 ; hsa-mir-4303 ; hsa-mir-4309 ; hsa-mir-4329 ; hsa-mir-4534 ; hsa-mir-4708-5p ; hsa-mir-4762-3p ; hsa-mir-4770 ; hsa-mir-6088 ; hsa-mir-6514-5p ; hsa-mir-6761-5p ; hsa-mir-8082

Nearest miRNA

hsa-mir-1265/Upstream/2429766; hsa-mir-107/Downstream/8282375;

Nearest TSS

Nearest CpG islands

None/Target, chr10-CpG: 68/Upstream/55027, chr10-CpG: 26/Downstream/47061

Upstream sequence

acaaagtacaaaacaaacattgtataatggagaccaaaaaaccaaaacatgcatttttgaaaatattattgaaactgataactttctggtgagactaaaa

Downstream sequence

acctccctgctggtggctcccacacttctgcttccagcccatcctggaccttggctgagcatgtccagctgctgacccactgttgctacttggttgtcaa