Basic Information
VIS ID
TVIS10018539
Fusion event
HBV-chr12 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1684
End
1846
Integrated sequence
TCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTC
Host Sequence
Chromosome
chr12
Cytoband
q12
Reference genome
GRCh37.55
Start
39661231/39267429 (Hg38)
End
39661231/39267429 (Hg38)
Nearest miRNA
hsa-mir-1244-3/Upstream/13393350; hsa-let-7i/Downstream/3056271;
Nearest TSS
ENST00000382841/Upstream/174555; ENST00000405531/Downstream/45397;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/121731, chr12-CpG: 120/Downstream/174980
Nearby gene
KIF21A
Upstream sequence
TGTTTGATTACATGGCTGACCACCTCCCGGGAACCGGTCTCCAGGCCCCTGTAGGCTAGAGGTTCAAAGCCCATCTTGCTGCAGTAGAATGACGTGGCCT
Downstream sequence
actcagtaatcacacagtcttttaacaaatccttgaaatctggtcaaaattaaccacttcctttcagttttctaatatagcacttacctcatttctgtaa
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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