Basic Information
VIS ID
TVIS10018540
Fusion event
HBV-chr12 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1584
End
1801
Integrated sequence
ACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCT
Host Sequence
Chromosome
chr12
Cytoband
q22
Reference genome
GRCh37.55
Start
92756850/92363074 (Hg38)
End
92756850/92363074 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA12B
Target gene
LINC02391 ; LOC105369902
Nearest miRNA
hsa-let-7i/Upstream/5617925; hsa-mir-1178/Downstream/2198715;
Nearest TSS
ENST00000382841/Upstream/216627; ENST00000508671/Downstream/758;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/216517, chr12-CpG: 133/Downstream/565492
Nearby gene
CLLU1OS
Upstream sequence
tgaagggagaagaaaattcataaaaaataaagcttggtcaaagcagaaggccaaaaaagaaaagaagaaaaaaatgaatgagaaaaggaaaagggaagaG
Downstream sequence
gccaatatggtgaaacacctctctactataaatacaaaaattagccaggcatggtggcacaggcctgtagtcccagctactcgagaggccgaggcaaaag
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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