Basic Information
VIS ID
TVIS10018541
Fusion event
HBV-chr12 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1411
End
1736
Integrated sequence
CGGGACGTCCTTTGTTTACGTCCCGTCGGCGCTGAATCCTGCGGACGACCCTTCTCGGGGTCGCTTGGGACTCTCTCGTCCCCTTCTCCGTCTGCCGTTCCGACCGACCACGGGGCGCACCTCTCTTTACGCGGACTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCACCAAATATTGCCCAAGGTCTTACATAAGAGGACT
Host Sequence
Chromosome
chr12
Cytoband
q23.1
Reference genome
GRCh37.55
Start
101109794/100716016 (Hg38)
End
101109794/100716016 (Hg38)
Nearest miRNA
hsa-let-7i/Upstream/526067; hsa-mir-1178/Downstream/3214409;
Nearest TSS
ENST00000382841/Upstream/92301; ENST00000551148/Downstream/1510;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/141949, chr12-CpG: 161/Downstream/69
Nearby gene
ANO4
Upstream sequence
GAGGAGACAGGGATCACAGGAGGTAGGAGTGAGGGATTTTTGCCATGCAGTTCTTGATACAGAGGATGGGCCAGGAGAAGGATCTCAGGTGTGCTCTCAC
Downstream sequence
GGTGTTTTGGTCTTCATGATATCTAGAAGAGGATTTTAAAGAAAAAGCAGTTTGGGAAGATCAAGGGTAATTTGGACATAGAATGGAAGAATTGGGTGGA
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
Curate