Basic Information
VIS ID
TVIS10018542
Fusion event
HBV-LOC107984625 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1883
Integrated sequence
TGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTG| |CCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAATTTGGAGCTACTGTGGAGTTACTCTCGTTTTTGCCTTCTGACTTCTTTCCTTCAGTA
Host Sequence
Chromosome
chr13
Cytoband
q21.2
Reference genome
GRCh37.55
Start
60108432/59534298 (Hg38)
End
60108432/59534298 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA13B ; FRA13C
Target gene
LOC107984625
Nearest miRNA
hsa-mir-1297/Upstream/4359750; hsa-mir-1267/Downstream/1665500;
Nearest TSS
ENST00000623511/Upstream/1301181; ENST00000435636/Downstream/161895;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/1899502, chr13-CpG: 52/Downstream/629228
Nearby gene
DIAPH3
Upstream sequence
GCATCTATAATTTCGTGTTTTAACAAAATTATTACACCAATTTTTTCTTATTGTTACACAGGATTGCATTTGATAATTGTATGTACTCGATGGTGTCTAA
Downstream sequence
TAGTATTTATTGCCTAATGATTACTAGAGAGGAGCCTCTTAAAGTATTTTGTGTTTTAATGAAAAAAACACCTCTTTAAAGCATTTGTGGCATGAGACAC
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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