Basic Information
VIS ID
TVIS10018544
Fusion event
HBV-chr14 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1697
Integrated sequence
TCTGCACGTCGCATGGAGACCACCGTGAACGCCCACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACC| |TTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATT
Host Sequence
Chromosome
chr14
Cytoband
q32.2
Reference genome
GRCh37.55
Start
99420302/98953965 (Hg38)
End
99420302/98953965 (Hg38)
Nearest miRNA
hsa-mir-1260a/Upstream/3815979; hsa-mir-1185-1/Downstream/1155454;
Nearest TSS
ENST00000550708/Upstream/26160; ENST00000423922/Downstream/204451;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/1734356, chr14-CpG: 53/Downstream/164103
Nearby gene
BCL11B
Nearest cancer related gene
BCL11B(OG, No orient)
Upstream sequence
CAAAATGTTTCTTCTCTCATATGGATTTATGGGATTCCCATCTCTTCAATATCCATTTCTCTCAATACCACCAGAAGAACTCATGGGAAACATCTTTAAT
Downstream sequence
GTGGAGAAGTGGAAACAGAAAGAGCCGCCTGTGCTGGCTGAGCAGCTCCCGGAGCAGGGCAGGAGGCCAGGCTCGTGGCACCAGGATCTCggggtatggc
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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