Basic Information
VIS ID
TVIS10018545
Fusion event
HBV-SNHG14 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1401
End
1891
Integrated sequence
GGATCCTGCGCGGGACGTCCTTTGTTTACGTCCCGTCGGCGCTGAATCCTGCGGACGACCCTTCTCGGGGTCGCTTGGGACTCTCTCGTCCCCTTCTCCGTCTGCCGTTCCGACCGACCACGGGGCGCACCTCTCTTTACGCGGACTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCACCAAATATTGCCCAAGGTCTTACA
Host Sequence
Chromosome
chr15
Cytoband
q11.2
Reference genome
GRCh37.55
Start
25555680/25310533 (Hg38)
End
25555680/25310533 (Hg38)
Location type
Intronic
Target gene
SNHG14
Nearest miRNA
hsa-mir-1268a/Upstream/1748402; hsa-mir-10393/Downstream/538214;
Nearest TSS
ENST00000557528/Upstream/222872; ENST00000557558/Downstream/35498;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/354626, chr15-CpG: 143/Downstream/127715
Nearby gene
UBE3A
Upstream sequence
AAGAGAATTGTGCATTTGTGCATGCAACCTCTGCCTGGGGAGGAAGAACCACTGCTCCTAATATGTCACCTAGGTCTCCCAGCACAAGGCTTACACAGCT
Downstream sequence
tttaaaagtctttatccaagttcaatttctatggttctgtagagatattttctgccagtttatgttcttcttttccatgggccatgttttcctgtttctt
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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