WWOX _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10018547
Fusion event
HBV-WWOX integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1825
Integrated sequence
TAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTT| |TTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGA
Host Sequence
Chromosome
chr16
Cytoband
q23.1
Reference genome
GRCh37.55
Start
78608617/78574720 (Hg38)
End
78608617/78574720 (Hg38)
Location type
Intron8
Target gene
WWOX
Nearest miRNA
hsa-mir-1225/Upstream/1705701; hsa-mir-11401/Downstream/2810298;
Nearest TSS
ENST00000527434/Upstream/68152; ENST00000566103/Downstream/503514;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/474551, chr16-CpG: 44/Downstream/1014874
Nearest cancer related gene
WWOX(TSG, No orient, 0)
Upstream sequence
TCCTGCAATCATTTTAAAGGCCTCCCAAATGGCGAGTGCTCCACGAACACACTTCAAAGAAAGAAATGAATGAATGAGCAGATTATTTTGGAATCACGTT
Downstream sequence
tgactaacaatgtggaatctgaaaaaaccaagctcatagaatagaaacagagagtgagaatggtggttgctggggctagggggtcagtgaagtggggagg
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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