PRKG1 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10018555
Fusion event
HBV-PRKG1 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1800
Integrated sequence
AGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGT| |CTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGG
Host Sequence
Chromosome
chr10
Cytoband
q21.1
Reference genome
GRCh37.55
Start
53556376/51796616 (Hg38)
End
53556376/51796616 (Hg38)
Location type
Intron3
Fragile sites / regions
FRA10G
Target gene
PRKG1
miRNAs that regulate target gene
hsa-mir-20a-5p ; hsa-mir-218-5p ; hsa-mir-3591-5p ; hsa-mir-1273e ; hsa-mir-921 ; hsa-mir-3606-5p
Nearest miRNA
hsa-mir-1265/Upstream/496961; hsa-mir-107/Downstream/2811258;
Nearest TSS
ENST00000439456/Upstream/97025; ENST00000646354/Downstream/250132;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/96617, chr10-CpG: 64/Downstream/517613
Upstream sequence
ggactgaatttactctcctgcctaaaacaactaaaaacaaaaacaaacaggcatttataagacaatggcttttaaacgttgtgctggacagtggtccttg
Downstream sequence
aaatcccaacaagacaaaaaaatgaaaaacacaCTGCCGCAGATCTTAGACATTGCTTATAAGATGCAAACTCAggccaggtgtggtggctcacgcttgt
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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