NBEAL1 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10018556
Fusion event
HBV-NBEAL1 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1815
Integrated sequence
ACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACC| |ATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACC
Host Sequence
Chromosome
chr2
Cytoband
q33.2
Reference genome
GRCh37.55
Start
204042073/203177350 (Hg38)
End
204042074/203177351 (Hg38)
Location type
Intron41
Fragile sites / regions
FRA2I
Target gene
NBEAL1
miRNAs that regulate target gene
hsa-mir-5089-3p ; hsa-mir-6864-3p ; hsa-mir-3672 ; hsa-mir-137 ; hsa-mir-873-3p ; hsa-mir-944 ; hsa-mir-7161-3p ; hsa-mir-3148 ; hsa-mir-3156-5p
Nearest miRNA
hsa-mir-10b/Upstream/14044239; hsa-mir-1244-1/Downstream/3605883;
Nearest TSS
ENST00000437798/Upstream/10040; ENST00000460355/Downstream/3605;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/162182, chr2-CpG: 78/Downstream/61390
Upstream sequence
gtggcaatttacttaactgctggggacctcgacggcttcatgtttatttgtttgtttatttttttgagacagggtctcactctgtcacccaggctggagt
Downstream sequence
tagtgagacgcccatctctattaaaaaaaaaaaaaaaGAGGAAGGGGGaagagttcttatatcttaataataaaaagacaacccaattaaaacatagaca
Target sequence
a
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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