VISDB Viral Integration Site DataBase

VIS ID

TVIS10018562

Fusion event

HBV-QKI integration

Validated

No

Detection method

VirusFinder

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2017

PubMed ID

Virus name

HBV

Reference genome

Start

1742

Integrated sequence

CCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGT| |TGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATC

Chromosome

chr6

Cytoband

q26

Reference genome

Start

End

163846559/163425527 (Hg38)

Location type

Intron1

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-214-3p ; hsa-mir-124-3p ; hsa-mir-425-5p ; hsa-mir-652-3p ; hsa-mir-331-3p ; hsa-mir-222-3p ; hsa-mir-100-5p ; hsa-let-7c-5p ; hsa-let-7b-5p ; hsa-let-7a-5p ; hsa-mir-17-5p ; hsa-mir-19a-3p ; hsa-mir-19b-3p ; hsa-mir-20a-5p ; hsa-mir-93-5p ; hsa-mir-106a-5p ; hsa-mir-181b-3p ; hsa-mir-224-5p ; hsa-mir-130a-3p ; hsa-mir-181b-2-3p ; hsa-mir-106b-5p ; hsa-mir-301a-3p ; hsa-mir-130b-3p ; hsa-mir-20b-5p ; hsa-mir-519c-3p ; hsa-mir-526b-3p ; hsa-mir-519b-3p ; hsa-mir-519d-3p ; hsa-mir-519a-3p ; hsa-mir-454-3p ; hsa-mir-301b-3p ; hsa-mir-548t-5p ; hsa-mir-4295 ; hsa-mir-3666 ; hsa-mir-4420 ; hsa-mir-5002-3p ; hsa-mir-548aw ; hsa-mir-548az-5p ; hsa-mir-141-3p ; hsa-mir-200a-3p ; hsa-mir-3607-3p ; hsa-mir-4668-3p ; hsa-mir-4722-3p ; hsa-mir-4769-3p ; hsa-mir-6727-3p ; hsa-mir-6817-5p ; hsa-mir-200b-3p ; hsa-mir-200c-3p ; hsa-mir-369-3p ; hsa-mir-429 ; hsa-mir-4282 ; hsa-mir-1277-5p ; hsa-mir-5011-5p ; hsa-mir-3161 ; hsa-mir-5689 ; hsa-mir-6776-3p ; hsa-mir-199a-3p ; hsa-mir-199b-3p ; hsa-mir-3129-5p ; hsa-mir-5582-5p ; hsa-mir-1468-3p ; hsa-mir-548f-5p ; hsa-mir-548g-5p ; hsa-mir-548x-5p ; hsa-mir-548aj-5p ; hsa-mir-6083 ; hsa-mir-302a-5p ; hsa-mir-8084 ; hsa-mir-1264 ; hsa-mir-455-5p ; hsa-mir-340-5p ; hsa-mir-6867-3p ; hsa-let-7d-3p ; hsa-mir-3684 ; hsa-mir-1909-5p ; hsa-mir-4685-3p ; hsa-mir-4287 ; hsa-mir-7113-3p ; hsa-mir-4469 ; hsa-mir-3692-3p ; hsa-mir-190a-3p ; hsa-mir-4801 ; hsa-mir-4731-3p ; hsa-mir-6747-3p ; hsa-mir-3910 ; hsa-mir-3714 ; hsa-mir-29a-3p ; hsa-mir-208a-3p ; hsa-mir-208b-3p ; hsa-mir-148a-3p

Nearest miRNA

hsa-mir-10398/Upstream/4660770; hsa-mir-1913/Downstream/3083827;

Nearest TSS

Nearest CpG islands

None/Target, chr6-CpG: 120/Upstream/9324, chr6-CpG: 64/Downstream/204926

Upstream sequence

AAACATTGCATAATGTTGACTTATTAAATAAAAATTACGTGTATATAGGAAATAAGGCTTTTGACAGGGAGAGACCCTTCTCTACCTCTGGACCTCGGTT

Downstream sequence

ATGAAGTGTGAAGAGTCAAACTATTATATACGTGGCTAACCCTTTAGGAAAATTTTTTGAGTAGTGATATTTTCTCAAAATAGtattaataaaaatattt

Target sequence

TTGG