VISDB Viral Integration Site DataBase

VIS ID

TVIS10018570

Fusion event

HBV-FN1 integration

Validated

No

Detection method

VirusFinder

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2017

PubMed ID

Virus name

HBV

Reference genome

Start

281

Integrated sequence

TAGGACCCCTTCTCGTGTTACAGGCGGGGTTTTTCTTGTTGACAAGAATCCTCACAATACCGCAGAGTCTAGACTCGTGGTGGACTTCTCTCAATTTTCT| |AGGGGGAACTACCGTGTGTCTTGGCCAAAATTCGCAGTCCCCAACCTCCAATCACTCACCAACCTCTTGTCCTCCAACTTGTCCTGGTTATCGCTGGATG

Chromosome

chr2

Cytoband

q35

Reference genome

Start

End

216269379/215404656 (Hg38)

Location type

Exon27

Target gene

miRNAs that regulate target gene

hsa-mir-200c-3p ; hsa-mir-200b-3p ; hsa-mir-1-3p ; hsa-let-7g-5p ; hsa-mir-26b-5p ; hsa-mir-615-3p ; hsa-mir-218-5p ; hsa-mir-140-3p

Nearest miRNA

hsa-mir-10b/Upstream/1646228; hsa-mir-1244-1/Downstream/2495857;

Nearest TSS

Nearest CpG islands

None/Target, chr2-CpG: 135/Upstream/91978, chr2-CpG: 43/Downstream/30888

Upstream sequence

GTCTCTTTTGTGGCTAATAATCCTGCTTTGGGAGTAGATCTGATTTCTGAAAATCATTTTGTATCCAAAATAATGTAAGCCTGTAAAGGAAAAACCTGAT

Downstream sequence

TAGGAAAAAAGATGAAACATGCCAAGAAATATTTAGATCAGTAATGATCATAACTCAAGTCCTGAAACTTGATTGAATGTCTAAGTTTTCTCTCCTCAAG

Target sequence

CGTGTGGTAAAGACTCCAGTGGCTTTGGGGCTCTCTTGGTTGCCCTTTATGGCCACGAGGGATACGGTGTACTCAGATGCAGGCTGCAGATTCCTCAGTGGGTACTTGGAGACAGAGGGACCCACATTGTACTGCCTGGGCTGTCCTCTTCGGGTAAGGCCCACGGTCAGTCGGTATCCTGTTATCTGGGCCCGAGGTGGAGTCCATCTCACCAGGACAGTAGAATCAGTTTCATTGACAAACTGGAGGTTAGTG