VISDB Viral Integration Site DataBase

VIS ID

TVIS10018572

Fusion event

HBV-FN1 integration

Validated

No

Detection method

VirusFinder

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2017

PubMed ID

Virus name

HBV

Reference genome

Start

458

Integrated sequence

CTTGTCCTGGTTATCGCTGGATGTGTCTGCGGCGTTTTATCATCTTCCTCTTCATCCTGCTGCTATGCCTCATCTTCTTGTTGGTTCTTCTGGACTATCA| |AGGTATGTTGCCCGTTTGTCCTCTAATTCCAGGATCCTCAACAACCAGCACGGGACCATGCCGGACCTGCATGACTACTGCTCAAGGAACCTCTATGTAT

Chromosome

chr2

Cytoband

q35

Reference genome

Start

End

216272277/215407554 (Hg38)

Location type

Intron29

Target gene

miRNAs that regulate target gene

hsa-mir-200c-3p ; hsa-mir-200b-3p ; hsa-mir-1-3p ; hsa-let-7g-5p ; hsa-mir-26b-5p ; hsa-mir-615-3p ; hsa-mir-218-5p ; hsa-mir-140-3p

Nearest miRNA

hsa-mir-10b/Upstream/1649163; hsa-mir-1244-1/Downstream/2492959;

Nearest TSS

Nearest CpG islands

None/Target, chr2-CpG: 135/Upstream/94913, chr2-CpG: 43/Downstream/27990

Upstream sequence

ttttttttttttttttttagagacagggtctcactgtcacccaggctggagtgcagtggcttgatcatagctcactgcagcctcaacctcctgggctcaa

Downstream sequence

AGACCTGACATCCTTAATAAATGTCAATTAGAGATGCCATTAGGTGAAAATATTCATGTTAAGCTGATTTTTCCTCTTTGAGCTCCAGACGAGGGAAGCA

Target sequence

TGCAGATTCATGAGCAAAAGTAAGATGCACTGTTTTCTTTGAGACAGAGGCTTAGAAACACCATAAATCCTCCCTTTTCTAATATCCCTTAGCATCTTGCTTGATTAGTGAAGAGCCAGTGATACTTTTTGACTCTTTGAATATTGCCACTTCTTCTAATAATGACTATTCAGCACGAAGATAAAATAAGAACAGTCATGCGAACCTTTTTAATAATAAATGTCATCCTTGA