IQGAP2 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10018575
Fusion event
HBV-IQGAP2 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
458
Integrated sequence
CTTGTCCTGGTTATCGCTGGATGTGTCTGCGGCGTTTTATCATCTTCCTCTTCATCCTGCTGCTATGCCTCATCTTCTTGTTGGTTCTTCTGGACTATCA| |AGGTATGTTGCCCGTTTGTCCTCTAATTCCAGGATCCTCAACAACCAGCACGGGACCATGCCGGACCTGCATGACTACTGCTCAAGGAACCTCTATGTAT
Host Sequence
Chromosome
chr5
Cytoband
q13.3
Reference genome
GRCh37.55
Start
75893261/76597436 (Hg38)
End
75893261/76597436 (Hg38)
Location type
Intron8
Target gene
IQGAP2
miRNAs that regulate target gene
hsa-mir-499a-5p ; hsa-mir-208b-3p ; hsa-mir-208a-3p ; hsa-mir-549a ; hsa-mir-641 ; hsa-mir-3617-5p ; hsa-mir-548e-5p ; hsa-mir-92a-1-5p
Nearest miRNA
hsa-mir-10397/Upstream/3718773; hsa-mir-103a-1/Downstream/6242719;
Nearest TSS
ENST00000502646/Upstream/362; ENST00000504254/Downstream/11534;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/193101, chr5-CpG: 111/Downstream/117859
Nearest cancer related gene
IQGAP2(TSG, No orient, 0)
Upstream sequence
TCTACATTTTGCTTAACTAAACTAGATGGAGCACTATTACCTGCTAGTACTCGGTGCTGATATTAACGAGGTGACAGCATCCAAAGTTCTCAGTTGTCAC
Downstream sequence
AGGGCAGGCTGCAGTGGACCATATCAATGCTGTCATTCCGGAAGGTGACCCCGAGAATACGCTGCTTGCACTGAAGAAACCAGAGGCCCAGCTGCCTGCT
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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