ZRANB3 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10018586
Fusion event
HBV-ZRANB3 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
901
Integrated sequence
TTACCAATTTTCTTTTGTCTTTGGGTATACATTTAAACCCTAACAAAACAAAGAGATGGGGTTACTCTCTAAATTTTATGGGTTATGTCATTGGATGTTA| |TGGGTCCTTGCCACAAGAACACATCATACAAAAAATCAAAGAATGTTTTAGAAAACTTCCTATTAACAGGCCTATTGATTGGAAAGTATGTCAACGAATT
Host Sequence
Chromosome
chr2
Cytoband
q21.3
Reference genome
GRCh37.55
Start
136005077/135247507 (Hg38)
End
136005077/135247507 (Hg38)
Location type
Intron9
Fragile sites / regions
FRA2S ; FRA2F
Target gene
ZRANB3
miRNAs that regulate target gene
hsa-mir-6855-5p ; hsa-mir-5096 ; hsa-mir-3170 ; hsa-mir-4662a-5p ; hsa-mir-193b-5p ; hsa-mir-6890-5p ; hsa-mir-575 ; hsa-mir-4676-5p ; hsa-mir-6858-3p
Nearest miRNA
hsa-mir-1285-2/Upstream/389634; hsa-mir-10b/Downstream/417890;
Nearest TSS
ENST00000437798/Upstream/8646; ENST00000483021/Downstream/106121;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/194819, chr2-CpG: 36/Downstream/283893
Upstream sequence
TACCAAGACACACACACTCTAACATGTAACCACCAGTCTCATGTGGTCTCCTCCAGGTGTCACCAATCTTGTAGGACTGACCCCCTTCATGGCAGCGGTC
Downstream sequence
TTTAAAACCCAAAGTAGTAAAAAAGAAAACGTTATTACTTATTATTATTTTTTTTTAGAGACATGGTCTTAGCCAGGTGCAGTGTCGCATGaagtgggag
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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