Basic Information
VIS ID
TVIS10018587
Fusion event
HBV-LOC105377989 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1822
Integrated sequence
GTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAAC| |TTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAA
Host Sequence
Chromosome
chr6
Cytoband
q22.33
Reference genome
GRCh37.55
Start
127223026/126901881 (Hg38)
End
127223028/126901883 (Hg38)
Location type
Intronic
Target gene
LOC105377989
Nearest miRNA
hsa-mir-10398/Upstream/417168; hsa-mir-1202/Downstream/4890289;
Nearest TSS
ENST00000381078/Upstream/561707; ENST00000485757/Downstream/216721;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/258039, chr6-CpG: 27/Downstream/216237
Nearby gene
RSPO3
Upstream sequence
CCTCGCCATGACCTGTAACCAGAGTGAGCACCAAAACAGCTAAGACAAAgcattgaccaatcaaatggatgctcactgtaaacaaccagtgtgactgtac
Downstream sequence
gttttataaacaaaatattattgaattcaaataaaattattcttaaaaatatacataacataaaaatataatttaatGACAAAAAGAACTCAGGTATGTA
Target sequence
tt
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
Curate