VISDB Viral Integration Site DataBase

VIS ID

TVIS10018589

Fusion event

HBV-ZNF516 integration

Validated

No

Detection method

VirusFinder

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Good

Reported year

2017

PubMed ID

Virus name

HBV

Reference genome

Start

110

Integrated sequence

CCTTCCACCAAACTCTGCAAGATCCCAGAGTGAGAGGCCTGTATTTCCCTGCTGGTGGCTCCAGTTCAGGAACAGTAAACCCTGTTCTGACTACTGCCTC| |TCCCTTATCGTCAATCTTCTCGAGGATTGGGGACCCTGCGCTGAACATGGAGAACATCACATCAGGATTCCTAGGACCCCTTCTCGTGTTACAGGCGGGG

Chromosome

chr18

Cytoband

q23

Reference genome

Start

End

74124950/76412994 (Hg38)

Location type

Intron5

Target gene

miRNAs that regulate target gene

hsa-mir-186-5p ; hsa-mir-432-3p ; hsa-mir-1277-5p ; hsa-mir-190a-3p ; hsa-mir-5011-5p ; hsa-mir-410-3p ; hsa-mir-5692c ; hsa-mir-5692b ; hsa-mir-6739-3p ; hsa-mir-4677-5p ; hsa-mir-7156-5p ; hsa-mir-4273 ; hsa-mir-489-3p ; hsa-mir-4256 ; hsa-mir-3913-3p ; hsa-mir-6719-3p ; hsa-mir-4526 ; hsa-mir-3660 ; hsa-mir-6730-3p ; hsa-mir-4286 ; hsa-mir-6729-3p ; hsa-mir-2114-5p ; hsa-mir-6873-3p ; hsa-mir-6881-3p ; hsa-mir-6780a-3p ; hsa-mir-7111-3p ; hsa-mir-6817-3p ; hsa-mir-7110-3p ; hsa-mir-6769b-3p ; hsa-mir-4723-3p ; hsa-mir-3183 ; hsa-mir-1306-5p ; hsa-mir-4699-3p ; hsa-mir-575 ; hsa-mir-4676-5p ; hsa-mir-6858-3p ; hsa-mir-1266-5p ; hsa-mir-1296-3p ; hsa-mir-1908-5p ; hsa-mir-211-3p ; hsa-mir-24-3p ; hsa-mir-3144-5p ; hsa-mir-3179 ; hsa-mir-3180-3p ; hsa-mir-3180 ; hsa-mir-3191-3p ; hsa-mir-3196 ; hsa-mir-3202 ; hsa-mir-3612 ; hsa-mir-3934-3p ; hsa-mir-4270 ; hsa-mir-4284 ; hsa-mir-4441 ; hsa-mir-4481 ; hsa-mir-4518 ; hsa-mir-4652-5p ; hsa-mir-4706 ; hsa-mir-4745-5p ; hsa-mir-4747-5p ; hsa-mir-4749-5p ; hsa-mir-491-5p ; hsa-mir-5196-5p ; hsa-mir-524-3p ; hsa-mir-525-3p ; hsa-mir-650 ; hsa-mir-663a ; hsa-mir-6754-5p ; hsa-mir-6777-5p ; hsa-mir-6787-5p ; hsa-mir-6797-5p ; hsa-mir-6810-5p ; hsa-mir-6816-5p ; hsa-mir-6825-5p ; hsa-mir-6889-5p ; hsa-mir-9500

Nearest miRNA

hsa-mir-1-2/Upstream/3559594;

Nearest TSS

Nearest CpG islands

None/Target, chr18-CpG: 67/Upstream/10141, chr18-CpG: 179/Downstream/28289

Upstream sequence

GCTTAAAATCAACAGCAACCATCCTATATATTTCTTTTAAATGAGGAAACTAGAGATTGTACACATTTTATCCACAGAGATCAAAAAAGGTTCTGCTTGC

Downstream sequence

AGGCCCACTTCTCCTTAGACATGAGACACTGCACCTGCCAAGGTAATGCTGAAACCAAGGCCTCTGTGAGGAAGCGGGAAGCGGAGGCAGAAACGAAGTG

Target sequence

ACAGTGAGCCCTGCTCAG