Basic Information
VIS ID
TVIS10018591
Fusion event
HBV-chr1 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1725
Integrated sequence
ACGCCCACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTT| |TAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTT
Host Sequence
Chromosome
chr1
Cytoband
p36.33
Reference genome
GRCh37.55
Start
747233/811853 (Hg38)
End
747233/811853 (Hg38)
Fragile sites / regions
FRA1A
Nearest miRNA
hsa-mir-12136/Upstream/179168; hsa-mir-101-1/Downstream/355251;
Nearest TSS
ENST00000473358/Upstream/6921; ENST00000326734/Downstream/5518;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/32686, chr1-CpG: 111/Downstream/15183
Nearby gene
FAM87B
Upstream sequence
ACTTATTTTAAATTCGTCTTGAAATATATTTGTAACTGTTATCAGTTGATTTGCTACTCAAAATGAACACTAGGTGGAACCACTTCTTTTTTTTCTATTC
Downstream sequence
tATATGTGGGGACAAAGTTTTTGAGGGCCTTGAACATCATTTAAAAGAGATTGGAATTTTTATCCTTAAGGTACTAGCTTGTAAACAGAAACTTTAGAGG
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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