Basic Information
VIS ID
TVIS10018592
Fusion event
HBV-chr1 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1572
Integrated sequence
CGCTTGGGACTCTCTCGTCCCCTTCTCCGTCTGCCGTTCCGACCGACCACGGGGCGCACCTCTCTTTACGCGGACTCCCCGTCTGTGCCTTCTCATCTGC| |CGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGA
Host Sequence
Chromosome
chr1
Cytoband
p22.1
Reference genome
GRCh37.55
Start
94444465/93978909 (Hg38)
End
94444465/93978909 (Hg38)
Fragile sites / regions
FRA1D
Nearest miRNA
hsa-mir-101-1/Upstream/131998; hsa-mir-11399/Downstream/564793;
Nearest TSS
ENST00000473358/Upstream/69453; ENST00000439455/Downstream/28843;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/68998, chr1-CpG: 93/Downstream/258225
Nearby gene
ABCA4
Upstream sequence
AATGTGTAACTCATCTGTCTTTGTGACTCAACCTCCACTAAAACAGCTGCACAGATTAATGCAGAACTGCTCCATAAGCTAATCTCAGTGTCTCTAAAGA
Downstream sequence
TGGAAGATGAACAAGAGATGAGGTGGTGGCAAAAAATAGGGATGATCTTAGACAAACTGAAACACTAAAAACAGCCTAAGTATGTTTCTtttctttttct
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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