Basic Information
VIS ID
TVIS10018593
Fusion event
HBV-chr1 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1793
Integrated sequence
GACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATA| |AATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGG
Host Sequence
Chromosome
chr1
Cytoband
p21.1
Reference genome
GRCh37.55
Start
105780294/105237672 (Hg38)
End
105780294/105237672 (Hg38)
Nearest miRNA
hsa-mir-101-1/Upstream/4956364; hsa-mir-11399/Downstream/2659551;
Nearest TSS
ENST00000473358/Upstream/1487266; ENST00000635102/Downstream/368331;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/1711381, chr1-CpG: 37/Downstream/843099
Nearby gene
LINC01676
Upstream sequence
CCCTGTGCAATTTAATTGACATGTGGCTAAAGCTTTGTGAGTCTTGTTGAACTTAACAGTTATATAATTTTCTTTGTATAATTTAAAAAAGGAAGTTCTC
Downstream sequence
TTCAAATATTGTTTACAAAGAAAATTAAAAAAGAAATATTAATCATTTAAAGATTATTGTAAAATCTCTGACTTTAAAATCTTAATAAGTAAAATGTTAG
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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