NBAS _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10018597
Fusion event
HBV-NBAS integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1821
Integrated sequence
TGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAA| |CTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATA
Host Sequence
Chromosome
chr2
Cytoband
p24.3
Reference genome
GRCh37.55
Start
15176605/15036481 (Hg38)
End
15176605/15036481 (Hg38)
Location type
Intronic
Target gene
NBAS
miRNAs that regulate target gene
hsa-mir-432-5p
Nearest miRNA
hsa-mir-3125/Upstream/2299037; hsa-mir-10b/Downstream/4311948;
Nearest TSS
ENST00000437798/Upstream/128817; ENST00000438178/Downstream/143897;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/400796, chr2-CpG: 27/Downstream/524534
Nearby gene
NBAS
Upstream sequence
tctgagattacatctgagcctgcgggaacctttccttttaatgacttaacggctgattgacactcaggattggcgtcttcgtatgccatcaactccacta
Downstream sequence
atgtaaaattccagcccaggcctgactccagaaactgagtcactttccacCTTAACACTCCCGAGTTCTGATTGAGCATGTTCTTTGTACAAGGAGCTAC
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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