Basic Information
VIS ID
TVIS10018602
Fusion event
HBV-chr2 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1820
Integrated sequence
TTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCA| |ACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTAT
Host Sequence
Chromosome
chr2
Cytoband
p11.2
Reference genome
GRCh37.55
Start
88363650/88064131 (Hg38)
End
88363655/88064136 (Hg38)
Fragile sites / regions
FRA2S ; FRA2L
Nearest miRNA
hsa-mir-1285-2/Upstream/434297; hsa-mir-10b/Downstream/18383;
Nearest TSS
ENST00000437798/Upstream/8402; ENST00000468008/Downstream/3644;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/8076, chr2-CpG: 63/Downstream/106036
Nearby gene
SMYD1
Upstream sequence
AGTTTACCTTAAAACCAATTCTTGGAGCAGGCGTCCATGTGATCACAATGGTGGTCTCAGTCACCTCGGTGTTGTAAGGTGGAATAGAGCTCCCAGGCTG
Downstream sequence
cttttccagtttcttggctcatggccgcttcttccatctttaaagtcagcaacacagccccttcaatatctctctgactctgaccctcttggttgcattg
Target sequence
ctggc
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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