Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10018603
Fusion event
HBV-TLK1 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
Virus Sequence
Virus name
HBV
Reference genome
Start
1631
Integrated sequence
CTCTCTTTACGCGGACTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCC| |ACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGA
Host Sequence
Chromosome
chr2
Cytoband
q31.1
Reference genome
End
172087053/171230543 (Hg38)
Location type
Intron20
Fragile sites / regions
Target gene
miRNAs that regulate target gene
hsa-mir-103a-3p ; hsa-mir-16-5p ; hsa-mir-28-5p ; hsa-mir-374b-3p ; hsa-mir-5696 ; hsa-mir-4524b-5p ; hsa-mir-4524a-5p ; hsa-mir-5581-5p ; hsa-mir-4297 ; hsa-mir-1909-5p ; hsa-mir-4729 ; hsa-mir-519e-3p ; hsa-mir-515-3p ; hsa-mir-33b-3p ; hsa-mir-646 ; hsa-mir-5586-3p ; hsa-mir-503-5p ; hsa-mir-15b-5p ; hsa-mir-15a-5p ; hsa-mir-195-5p ; hsa-mir-424-5p ; hsa-mir-497-5p ; hsa-mir-6838-5p ; hsa-mir-1305 ; hsa-mir-421 ; hsa-mir-505-3p ; hsa-mir-7159-5p ; hsa-mir-4660 ; hsa-mir-153-5p ; hsa-mir-1250-3p ; hsa-mir-4801 ; hsa-mir-4731-3p
Nearest miRNA
hsa-mir-128-1/Upstream/2647525; hsa-mir-10b/Downstream/3937090;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/69193, chr2-CpG: 104/Downstream/203311
Upstream sequence
TGCATTTATACTAAATTATGAATGGCTGGCAAGACAAAGAATTAGTCTCCAGAGTTATACAAACAGGGATTAAAAAGTGTTCAGACTCCAGTCTCAACTC
Downstream sequence
acaatctccacactttggaccactctaaaacccctaaacaccctagccccagactcctcagggagatagatttgagatttcctcccgtctccttgttcaa
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.