Basic Information
VIS ID
TVIS10018610
Fusion event
HBV-LOC105374686 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1819
Integrated sequence
TTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGC| |AACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTA
Host Sequence
Chromosome
chr5
Cytoband
p14.3
Reference genome
GRCh37.55
Start
23079892/23079783 (Hg38)
End
23079892/23079783 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA5E
Target gene
LOC105374686
Nearest miRNA
hsa-mir-10397/Upstream/5923791; hsa-mir-103a-1/Downstream/8856319;
Nearest TSS
ENST00000502646/Upstream/66735; ENST00000502755/Downstream/363803;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/1620040, chr5-CpG: 68/Downstream/2110611
Nearby gene
PRDM9
Upstream sequence
AACTTAATAGAAGTTAATTAGATTTTTCTAGAAAACATTATAAAATTGCCTGCACAAACACATACGCACAAGCTATAGCCATAATATTAAAAATAAAGTG
Downstream sequence
caacatctagagacactttaaattgtcacaattcaggtgcatacttcaggaatagatgccagggatgctactaagcatcttacaatgcacaggacaaccc
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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