RASGRF2 _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10018612
Fusion event
HBV-RASGRF2 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1805
Integrated sequence
TACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCG| |CACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATG
Host Sequence
Chromosome
chr5
Cytoband
q14.1
Reference genome
GRCh37.55
Start
80465337/81169518 (Hg38)
End
80465348/81169529 (Hg38)
Location type
Intron17
Target gene
RASGRF2
Nearest miRNA
hsa-mir-10397/Upstream/8290855; hsa-mir-103a-1/Downstream/1670626;
Nearest TSS
ENST00000502646/Upstream/54666; ENST00000505704/Downstream/63756;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/208331, chr5-CpG: 39/Downstream/131972
Upstream sequence
TGCTCCCTACAGTTCACTGTGACTCTCTGAGTTCGTACAGCCTATGAAAGCTGTCCAGAGAATGCAGCACTGGCCTCACCAGTAGTATTTTTAACGGCAG
Downstream sequence
tcttccctctaggtgtgtctgtgtccaaatttccctcttataatgattaggacgcaccataatccactttgacatcttaacttggtcacatctgcaaaga
Target sequence
tcacatggtct
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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