Basic Information
VIS ID
TVIS10018613
Fusion event
HBV-chr6 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
891
Integrated sequence
TTTACCGCTGTTACCAATTTTCTTTTGTCTTTGGGTATACATTTAAACCCTAACAAAACAAAGAGATGGGGTTACTCTCTAAATTTTATGGGTTATGTCA| |TTGGATGTTATGGGTCCTTGCCACAAGAACACATCATACAAAAAATCAAAGAATGTTTTAGAAAACTTCCTATTAACAGGCCTATTGATTGGAAAGTATG
Host Sequence
Chromosome
chr6
Cytoband
p25.3
Reference genome
GRCh37.55
Start
284509/284509 (Hg38)
End
284509/284509 (Hg38)
Location type
Intronic
Target gene
LOC102723922 ; LOC107986553
Nearest miRNA
hsa-mir-10398/Downstream/1105805;
Nearest TSS
ENST00000381078/Upstream/79025; ENST00000603290/Downstream/7121;
Nearest CpG islands
None/Target, None/Upstream, chr6-CpG: 120/Downstream/7439
Nearby gene
DUSP22
Upstream sequence
ctatgtgcatttcacaatagggtttgtgctcctatgagaatctggtatgtcgctgatcagacaggaggcggagctcagatggtaatacttgcctcctgcA
Downstream sequence
AAAAGATCAAAATGTGTTTTTCTCCATGAAGAAAGATCAAAATGTGTTTTTCTCCATGAAGAAATATTGACATCGACGTTTCCTCAGCCATTATTTCCCT
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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