Basic Information
VIS ID
TVIS10018616
Fusion event
HBV-chr6 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1826
Integrated sequence
AAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTT| |TCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGAA
Host Sequence
Chromosome
chr6
Cytoband
q15
Reference genome
GRCh37.55
Start
91801522/91091804 (Hg38)
End
91801522/91091804 (Hg38)
Fragile sites / regions
FRA6G
Nearest miRNA
hsa-mir-10398/Upstream/778971; hsa-mir-1202/Downstream/429856;
Nearest TSS
ENST00000381078/Upstream/504759; ENST00000452624/Downstream/301196;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/480304, chr6-CpG: 92/Downstream/2324750
Nearby gene
MIR4643
Upstream sequence
TTAGGCTCACCAATACTTTCTGACAAAGAAAAAAAAATGTTAGCATATGTTTAACCAAACCCTTTCTTTCCTTCATCCTTCTTATCAAAGTAGAGGCATG
Downstream sequence
caagtccacttctgggtatatatccaaaagaattggaggccgggactcgcacagatacgtgtacacccatgttcatagcaacattattcacaatagctga
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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