Basic Information
VIS ID
TVIS10018626
Fusion event
HBV-chr8 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1789
Integrated sequence
GACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGG| |CATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGG
Host Sequence
Chromosome
chr8
Cytoband
q21.13
Reference genome
GRCh37.55
Start
79005059/78092824 (Hg38)
End
79005059/78092824 (Hg38)
Nearest miRNA
hsa-mir-124-1/Upstream/1125974; hsa-mir-10400/Downstream/1239364;
Nearest TSS
ENST00000518652/Upstream/642127; ENST00000521879/Downstream/55277;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/1092003, chr8-CpG: 46/Downstream/423374
Nearby gene
PKIA
Upstream sequence
ttcatgagcggattaatgtctttgtttctggagtaggtttcttataaaagcaactttggccctctcttgctttctcttgcacattctttcaccatgtgat
Downstream sequence
ttgaatttcttcatcgataaaatgaggataataatatttcatagagttgttttgaggaatgttatgtagttttaaaatgttaattcattaacttaaatca
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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