Basic Information
VIS ID
TVIS10018629
Fusion event
HBV-chr8 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1825
Integrated sequence
TAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTT| |TTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACCCTTATAAAGA
Host Sequence
Chromosome
chr8
Cytoband
q24.12
Reference genome
GRCh37.55
Start
122474298/121462058 (Hg38)
End
122474298/121462058 (Hg38)
Fragile sites / regions
FRA8C ; FRA8E
Nearest miRNA
hsa-mir-12123/Upstream/2136793; hsa-mir-10400/Downstream/1753730;
Nearest TSS
ENST00000518652/Upstream/548993; ENST00000522197/Downstream/177235;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/649578, chr8-CpG: 64/Downstream/177367
Nearby gene
HAS2
Upstream sequence
TTCAATACAGAAAAGGTTATTTGAAGGTATCTACTGTACTGTTTAACCTTTCTTAGAAATGCCACCAGCAACATTACCACTTCCTGACACCCCAAATAGC
Downstream sequence
tcagaaataaacacaaacatagacagtcaagtaaattttgatacggccactaagaagacacaatgggaaaaggatagtcccttcaaaaagtagtgttggg
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
Curate