GLDC _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10018630
Fusion event
HBV-GLDC integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1813
Integrated sequence
AGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCA| |CCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGA
Host Sequence
Chromosome
chr9
Cytoband
p24.1
Reference genome
GRCh37.55
Start
6594785/6594785 (Hg38)
End
6594785/6594785 (Hg38)
Location type
Intron16
Target gene
GLDC
miRNAs that regulate target gene
hsa-mir-423-3p
Nearest miRNA
hsa-mir-101-2/Upstream/586881; hsa-let-7a-1/Downstream/11978521;
Nearest TSS
ENST00000422679/Upstream/1691; ENST00000413145/Downstream/10012;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/180688, chr9-CpG: 63/Downstream/50295
Upstream sequence
ATACAAATGCCAAGATACTACACAAAACATCCACAGGAACTTTTTTCATCTTTTTTTTTTTTGAATTGTACACAAACATTTCCTACATAATCCAACATAC
Downstream sequence
TTTGACCATTCCCCATACACTGAAGAAAAGACAACATTTACTCAATTATTCTTTATAGGGCATCATTTATTCAATCATGTTTTAACATGTAAAGCATTGG
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
Curate