Basic Information
VIS ID
TVIS10018632
Fusion event
HBV-chr10 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1797
Integrated sequence
TTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATT| |GGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTT
Host Sequence
Chromosome
chr10
Cytoband
p12.31
Reference genome
GRCh37.55
Start
21000749/20711820 (Hg38)
End
21000749/20711820 (Hg38)
Nearest miRNA
hsa-mir-1265/Upstream/159774; hsa-mir-107/Downstream/784742;
Nearest TSS
ENST00000439456/Upstream/620036; ENST00000417845/Downstream/104005;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/893803, chr10-CpG: 149/Downstream/461379
Nearby gene
NEBL
Upstream sequence
gtgccactgcactccagcctgggtgacagagagagactccgtgtgaaaaaaaaaaaaaaaaTACCAGGTCTGGTTTTTGAAATTCTTTCTCCGTATTAAA
Downstream sequence
ggggaaggggaaggggaaaggaagggaaagggaagaggaaggggaagggggaagaggaaggggaacagaacaagaaaggggaggggaaagggaaggggaa
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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