Basic Information
VIS ID
TVIS10018641
Fusion event
HBV-HERC2P3 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1788
Integrated sequence
CGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAG| |GCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTG
Host Sequence
Chromosome
chr15
Cytoband
q11.1
Reference genome
GRCh37.55
Start
20614120/20408867 (Hg38)
End
20614120/20408867 (Hg38)
Location type
Intron1
Target gene
HERC2P3
Nearest miRNA
hsa-mir-10393/Downstream/423928;
Nearest TSS
ENST00000557528/Upstream/56506; ENST00000560839/Downstream/132933;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/49911, chr15-CpG: 58/Downstream/97244
Upstream sequence
GTAGGTTAGGTAGGTGGCGCACATAGGCTACTCCAGGAGAAAGTTGttctttttttttcttttttttttttttttttgagacagagtttcactcttgttg
Downstream sequence
TCAAAAAGCTCATTACCAATTTATGAAAAGCAGCAAAACTCATTTTCTCTTAATGTGAAATCACTTCAGCCTGTCAGTAGAGAAAGAATTGTTGAAAAGT
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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