Basic Information
VIS ID
TVIS10018643
Fusion event
HBV-chr15 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1768
Integrated sequence
TGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTC| |TTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCA
Host Sequence
Chromosome
chr15
Cytoband
q13.3
Reference genome
GRCh37.55
Start
32549108/32256907 (Hg38)
End
32549108/32256907 (Hg38)
Nearest miRNA
hsa-mir-1268a/Upstream/1191766; hsa-mir-10393/Downstream/2125162;
Nearest TSS
ENST00000557528/Upstream/98321; ENST00000568289/Downstream/102631;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/88444, chr15-CpG: 308/Downstream/55539
Nearby gene
GOLGA8K
Upstream sequence
ATCAACTTATTTGGTATTTTTTTCTCAGCTTATTGTTACAGACATGTTAGTGGCAAATCTGAGAAGGTTCTTTTGTGAATCAGGTTATGGCTATGATTGT
Downstream sequence
ATGACTACTGAAATGCTTCTATTAAAATATCAATTATCAAAATATTTCAACCCCACACTTCTCCACCAAGGCTGGCTTTGCTGTACCTTAAGCCTGAGTT
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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