Basic Information
VIS ID
TVIS10018645
Fusion event
HBV-chr17 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1388
End
1876
Integrated sequence
TGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTTTACGTCCCGTCGGCGCTGAATCCTGCGGACGACCCTTCTCGGGGTCGCTTGGGACTCTCTCGTCCCCTTCTCCGTCTGCCGTTCCGACCGACCACGGGGCGCACCTCTCTTTACGCGGACTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCACCAAATATTGC
Host Sequence
Chromosome
chr17
Cytoband
q21.2
Reference genome
GRCh37.55
Start
39266276/41110024 (Hg38)
End
39266335/41110083 (Hg38)
Nearest miRNA
hsa-mir-1180/Upstream/916361; hsa-mir-10226/Downstream/407081;
Nearest TSS
ENST00000595228/Upstream/4635; ENST00000635603/Downstream/8277;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/246175, chr17-CpG: 83/Downstream/417573
Nearby gene
KRTAP4-9
Upstream sequence
aaaaataaaTagacttagctcccccaaggatactgtcttccctacatgcctctcaaatggtggctattgctccattcactaaccaagtacaactataacg
Downstream sequence
agaaagaaagaaagaaagaaagaaagaaagaaaagaaaaagaaagaaaagaagagccttaaggtcaacctacaaactacagagttcctaagttctctttt
Target sequence
gaaagcaagcaagcaagaaagcaagcaagcaagaaagaaagaaagaaagaaagaaagaa
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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