Basic Information
VIS ID
TVIS10018646
Fusion event
HBV-PIEZO2 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1795
Integrated sequence
CCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAA| |TTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCT
Host Sequence
Chromosome
chr18
Cytoband
p11.21
Reference genome
GRCh37.55
Start
11054772/11054773 (Hg38)
End
11054772/11054773 (Hg38)
Location type
Intron50
Target gene
PIEZO2
Nearest miRNA
hsa-mir-3976/Upstream/295124; hsa-mir-1-2/Downstream/600112;
Nearest TSS
ENST00000575820/Upstream/161156; ENST00000591029/Downstream/93815;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/328104, chr18-CpG: 169/Downstream/93535
Upstream sequence
TGAGTGTGGCATCCTCCCTCCACCTCGCCCACCTCTGAGTCCCGCCATAACCTACCCGGAACCTACCAGAACCTAGCATCACTGCACGCCACCGCGGCCC
Downstream sequence
GAGTTGGATACGGTTGAGAGAATGCCAAGCCCAGGGAGAGGAGCATGGATGAGATGATCCTGGGGTGTGGGGGACTTGCTAGACTGATGAGGCACTCCTG
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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