Basic Information
VIS ID
TVIS10018655
Fusion event
HBV-chr2 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1751
Integrated sequence
TTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGG| |AGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGT
Host Sequence
Chromosome
chr2
Cytoband
p11.2
Reference genome
GRCh37.55
Start
83990500/83763376 (Hg38)
End
83990500/83763376 (Hg38)
Fragile sites / regions
FRA2S ; FRA2L
Nearest miRNA
hsa-mir-1285-2/Upstream/3896793; hsa-mir-10b/Downstream/2020224;
Nearest TSS
ENST00000437798/Upstream/240562; ENST00000440495/Downstream/551732;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/2295819, chr2-CpG: 27/Downstream/527214
Nearby gene
FUNDC2P2
Upstream sequence
CACGTGCACCTCATCATGTGACCCATGTCATGCTGCTTATCCCACTGATCTCCAATGCGGTACATGACCCCTTCATTGGTTGTGCAGATTTCCTCGTGGG
Downstream sequence
TGTAATAACTTACAAATCAACAATATTTGGTTTTGCAGAGCAGGAAGGGAATTTGAGATAGCTGTTCCTTTCCTATTTCTCTCTTCCAGAAATACAAAAG
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
Curate