Basic Information
VIS ID
TVIS10018659
Fusion event
HBV-chr6 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
848
Integrated sequence
TGTGGTATTGGGGGCCAAGTCTGTACAGCATCTTGAGTCCCTTTTTACCGCTGTTACCAATTTTCTTTTGTCTTTGGGTATACATTTAAACCCTAACAAA| |ACAAAGAGATGGGGTTACTCTCTAAATTTTATGGGTTATGTCATTGGATGTTATGGGTCCTTGCCACAAGAACACATCATACAAAAAATCAAAGAATGTT
Host Sequence
Chromosome
chr6
Cytoband
p22.3
Reference genome
GRCh37.55
Start
25188456/25188228 (Hg38)
End
25188456/25188228 (Hg38)
Nearest miRNA
hsa-mir-3691/Upstream/6616348; hsa-mir-10398/Downstream/1959398;
Nearest TSS
ENST00000381078/Upstream/131155; ENST00000461945/Downstream/90850;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/48210, chr6-CpG: 76/Downstream/90675
Nearby gene
LOC101928663
Upstream sequence
ACTAATGTTTTCCCATATTAACTCAGAATAACTTTGTCTGAAATTAAACTGAATATATATCATTTATAGATACAAGCATAGAGTTTAAATTCAGGTAATC
Downstream sequence
ATTTATCAGTCTCTTCACCACATGCCCATCAATTATATTTAGCAATATaatacgtactgaggacttttgataagaggtatgttccttctgatttatacat
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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