Basic Information
VIS ID
TVIS10018660
Fusion event
HBV-chr8 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1815
Integrated sequence
ACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCACC| |ATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGACC
Host Sequence
Chromosome
chr8
Cytoband
q24.13
Reference genome
GRCh37.55
Start
125905676/124893434 (Hg38)
End
125905676/124893434 (Hg38)
Fragile sites / regions
FRA8C ; FRA8E
Nearest miRNA
hsa-mir-12123/Upstream/71376; hsa-mir-10400/Downstream/2902528;
Nearest TSS
ENST00000518652/Upstream/35918; ENST00000533286/Downstream/46915;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/164409, chr8-CpG: 103/Downstream/104621
Nearby gene
LINC00964
Upstream sequence
cacatgtggctaatttttgtgtttttagtagagacaggatttcaccatgttgttcagctagtctcaaattcctgacctcaggtgatccatccaccttggc
Downstream sequence
ACCTGGATTTTCTGTGAGTGTGGGGAAGGCTGGTGGTGGTAGTGACGCAGGTGTAAAGGAGATGCATTTATGAAAAGAAAAAGCAAAAACTGGTGAAAAA
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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