Basic Information
VIS ID
TVIS10018661
Fusion event
HBV-LOC105369976 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1814
Integrated sequence
GACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCACCAGCAC| |CATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGACATCGAC
Host Sequence
Chromosome
chr12
Cytoband
q24.11
Reference genome
GRCh37.55
Start
110520921/110083116 (Hg38)
End
110520921/110083116 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA12E
Target gene
LOC105369976
Nearest miRNA
hsa-let-7i/Upstream/249680; hsa-mir-1178/Downstream/1221026;
Nearest TSS
ENST00000382841/Upstream/9430; ENST00000549009/Downstream/41219;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/34347, chr12-CpG: 45/Downstream/41217
Nearby gene
IFT81
Upstream sequence
TAAATTTTTTAAAAAACAATTTACTTTAAACTTGAAAATTTACTGATTTGACTAAAAAAATTTTGAAAATCTAAAATGTATTTTAAAATATTACTTCCtt
Downstream sequence
TAGGTGGGAGGACTGACGGGCTCCAGTCCTTCGGCAACACCAATTCTGTCTGCACTCCCCAGGTCTGTCAGTCCCTCCCCCTCCTGTCATTGTTCCCAGG
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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