Basic Information
VIS ID
TVIS10018663
Fusion event
HBV-chr14 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1482
End
1787
Integrated sequence
TCTCTCGTCCCCTTCTCCGTCTGCCGTTCCGACCGACCACGGGGCGCACCTCTCTTTACGCGGACTCCCCGTCTGTGCCTTCTCATCTGCCGGACCGTGTGCACTTCGCTTCACCTCTGCACGTCGCATGGAGACCACCGTGAACGCCCACCAAATATTGCCCAAGGTCTTACATAAGAGGACTCTTGGACTCTCAGCAATGTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGA
Host Sequence
Chromosome
chr14
Cytoband
q12
Reference genome
GRCh37.55
Start
25171137/24701931 (Hg38)
End
25171137/24701931 (Hg38)
Nearest miRNA
hsa-mir-208a/Upstream/558366; hsa-mir-1185-1/Downstream/2206711;
Nearest TSS
ENST00000550708/Upstream/67664; ENST00000547786/Downstream/117546;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/271759, chr14-CpG: 125/Downstream/347287
Nearby gene
GZMB
Upstream sequence
tcccagcctcttataatgccaactcttttcccttgttaccccagcctgaagtattctaaaatagctgtatcctacattaatgtctggattacatcacctt
Downstream sequence
tacagtgatgtttctcatggcagtggggttataaatagtcaagtaatttttcccatgtactttattatattttctaaatcttccacaaaagcacatatga
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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