Basic Information
VIS ID
TVIS10018665
Fusion event
HBV-LOC105373318 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
447
Integrated sequence
TTGTCCTCCAACTTGTCCTGGTTATCGCTGGATGTGTCTGCGGCGTTTTATCATCTTCCTCTTCATCCTGCTGCTATGCCTCATCTTCTTGTTGGTTCTT| |CTGGACTATCAAGGTATGTTGCCCGTTTGTCCTCTAATTCCAGGATCCTCAACAACCAGCACGGGACCATGCCGGACCTGCATGACTACTGCTCAAGGAA
Host Sequence
Chromosome
chr1
Cytoband
q44
Reference genome
GRCh37.55
Start
249229632/248935433 (Hg38)
End
249229632/248935433 (Hg38)
Location type
Intronic
Fragile sites / regions
FRA1I
Target gene
LOC105373318
Nearest miRNA
hsa-mir-101-1/Upstream/108990;
Nearest TSS
ENST00000473358/Upstream/29061;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/28642, None/Downstream
Nearby gene
PGBD2
Upstream sequence
ttacattatttgcccCAATTTGCTCCTATCTGCCCTATTCCAAGGCCCAAACTTGCTTCTCTGATACTAAGTATCAACAGAAACTACCATCATGACTAGT
Downstream sequence
ACTAATATTAGGTATATTTTCTAATTCTTGTTATTCTGATCGTTAGCGCTTAAAAAGAGTTTGTGTTTTATGTTCTAAGTTGGCAATGTAGTTAGGGAAG
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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