Basic Information
VIS ID
TVIS10018669
Fusion event
HBV-LOC105377703 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
54
End
470
Integrated sequence
TTCCCTGCTGGTGGCTCCAGTTCAGGAACAGTAAACCCTGTTCTGACTACTGCCTCTCCCTTATCGTCAATCTTCTCGAGGATTGGGGACCCTGCGCTGAACATGGAGAACATCACATCAGGATTCCTAGGACCCCTTCTCGTGTTACAGGCGGGGTTTTTCTTGTTGACAAGAATCCTCACAATACCGCAGAGTCTAGACTCGTGGTGGACTTCTCTCAATTTTCTAGGGGGAACTACCGTGTGTCTTGGCCAA
Host Sequence
Chromosome
chr5
Cytoband
q34
Reference genome
GRCh37.55
Start
163732086/164305080 (Hg38)
End
163732086/164305080 (Hg38)
Location type
Intronic
Target gene
LOC105377703
Nearest miRNA
hsa-mir-10397/Upstream/3819630; hsa-mir-103a-1/Downstream/3860765;
Nearest TSS
ENST00000502646/Upstream/7951; ENST00000519901/Downstream/49060;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/799140, chr5-CpG: 17/Downstream/2673399
Nearby gene
LINC02143
Upstream sequence
aagagaaggtgtgcaggggaactcccctttacaaaactatcagatctcatgagactcactcaatatgatgagaacagtactggaaataccatgcccccat
Downstream sequence
TGTGTTAAGAAACAAGAACCAGTTAGTTACCTTTGGATTTCCTGCACTATTACTTTGGTTTAAGGCAATCGTGGAGATAAGCAGTTGGAGTTGCAGGTCA
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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