SH2D4B _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10018670
Fusion event
HBV-SH2D4B integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
2521
Integrated sequence
AGAAGATCTCAATCTCGGGAATCTCAATGTTAGTATTCCTTGGACTCATAAGGTGGGGAACTTTACTGGGCTTTATTCTTCTACTGTACCTGTCTTTAAT| |CCTCATTGGAAAACACCATCTTTTCCTAATATACATTTACACCAAGACATTATCAAAAAATGTGAACAGTTTGTAGGCCCACTCACAGTTAATGAGAAAA
Host Sequence
Chromosome
chr10
Cytoband
q23.1
Reference genome
GRCh37.55
Start
82386704/80626948 (Hg38)
End
82386704/80626948 (Hg38)
Location type
Intron6
Fragile sites / regions
FRA10D
Target gene
SH2D4B
Nearest miRNA
hsa-mir-1265/Upstream/5074395; hsa-mir-107/Downstream/5637746;
Nearest TSS
ENST00000439456/Upstream/19649; ENST00000481537/Downstream/16048;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/90512, chr10-CpG: 149/Downstream/1247345
Upstream sequence
gtcagagtgccatgtgactcccggttcgttagctccagcagggaagcaagtcaaagagagctagtgtccccggttcaatgcctaactagaattctgccta
Downstream sequence
gtctgtaattccagcacttggggaggctgtggcaggaggatcacttttgctcaggatttcTAATAATAGTAACTATTACTAGAGACCTGATAATAATTAT
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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