Basic Information
VIS ID
TVIS10018671
Fusion event
HBV-chr11 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
3033
Integrated sequence
AATCCAGATTGGGACTTCAATCCCAACAAGGACACCTGGCCAGACGCCAACAAGGTAGGAGCTGGAGCATTCGGGCTGGGTTTCACCCCACCGCACGGAG| |GCCTTTTGGGGTGGAGCCCTCAGGCTCAGGGCATACTACAAACTTTGCCAGCAAATCCGCCTCCTGCCTCCACCAATCGCCAGTCAGGAAGGCAGCCTAC
Host Sequence
Chromosome
chr11
Cytoband
q25
Reference genome
GRCh37.55
Start
131229644/131359749 (Hg38)
End
131229644/131359749 (Hg38)
Nearest miRNA
hsa-let-7a-2/Upstream/692946; hsa-mir-4697/Downstream/2538755;
Nearest TSS
ENST00000527297/Upstream/106303; ENST00000416661/Downstream/10729;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/443010, chr11-CpG: 16/Downstream/330713
Nearby gene
NTM
Upstream sequence
ggatataaatatatatgtatatatataatttcatttaatcagaacaatcctacaaagcaaaattttgcctcattttacagagtaaaacctgagacttaga
Downstream sequence
tggaaactggctggggctggggtttcaccagcatccagagaccctgataagtctcccagcaacaGTCTGGGCAGGTGAATTTATCACCTTGACTGGAAAG
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
Curate