HP _LIHC.png
Expression analysis of TCGA samples
Basic Information
VIS ID
TVIS10018675
Fusion event
HBV-HP integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Tumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Good
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1186
End
1645
Integrated sequence
TGCTGACGCAACCCCCACTGGCTGGGGCTTGGTCATGGGCCATCAGCGCATGCGTGGAACCTTTTCGGCTCCTCTGCCGATCCATACTGCGGAACTCCTAGCCGCTTGTTTTGCTCGCAGCAGGTCTGGAGCAAACATTATCGGGACTGATAACTCTGTTGTCCTATCCCGCAAATATACATCGTTTCCATGGCTGCTAGGCTGTGCTGCCAACTGGATCCTGCGCGGGACGTCCTTTGTTTACGTCCCGTCGGC
Host Sequence
Chromosome
chr16
Cytoband
q22.2
Reference genome
GRCh37.55
Start
72093011/72059112 (Hg38)
End
72093086/72059187 (Hg38)
Location type
Exon6
Target gene
HP
Nearest miRNA
hsa-mir-1225/Upstream/2028690; hsa-mir-11401/Downstream/4809749;
Nearest TSS
ENST00000527434/Upstream/2951; ENST00000566168/Downstream/4037;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/50123, chr16-CpG: 15/Downstream/34043
Upstream sequence
CACACCTGCCCCCCATACCCCTTCCTCCAGGAGATACTTGAGAGGGACCATGCCCGGCTGAAGCCCCGTCTCGTGTGGAAGAATGTCATCTCCAGTGTCT
Downstream sequence
GGTGGGTGCTGAGCACTTAAGAGAGCAGGCAGGCGTCCAGCGGGGAACGTCCTAGAGGCACAGCCTTCCAGTGCGGCTTCCTCTGAGCACACAAGAGCCA
Target sequence
GGAGTGTACACCTTAAACAATGAGAAGCAGTGGATAAATAAGGCTGTTGGAGATAAACTTCCTGAATGTGAAGCA
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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