VISDB Viral Integration Site DataBase

VIS ID

TVIS10018676

Fusion event

HBV-APOH integration

Validated

No

Detection method

VirusFinder

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HBV

Reference genome

Start

11

End

1013

Integrated sequence

CTTCCACCAAACTCTGCAAGATCCCAGAGTGAGAGGCCTGTATTTCCCTGCTGGTGGCTCCAGTTCAGGAACAGTAAACCCTGTTCTGACTACTGCCTCTCCCTTATCGTCAATCTTCTCGAGGATTGGGGACCCTGCGCTGAACATGGAGAACATCACATCAGGATTCCTAGGACCCCTTCTCGTGTTACAGGCGGGGTTTTTCTTGTTGACAAGAATCCTCACAATACCGCAGAGTCTAGACTCGTGGTGGAC

Chromosome

chr17

Cytoband

q24.2

Reference genome

Start

End

64216671/66220553 (Hg38)

Location type

Exon4

Target gene

miRNAs that regulate target gene

hsa-mir-335-5p ; hsa-mir-6738-3p ; hsa-mir-640 ; hsa-mir-5001-3p ; hsa-mir-4727-5p ; hsa-mir-103a-2-5p ; hsa-mir-6821-3p ; hsa-mir-6790-3p ; hsa-mir-3934-5p ; hsa-mir-764 ; hsa-mir-125a-3p ; hsa-mir-6836-3p ; hsa-mir-6829-3p ; hsa-mir-6791-3p ; hsa-mir-6778-3p ; hsa-mir-150-5p ; hsa-mir-186-3p ; hsa-mir-520h ; hsa-mir-520g-3p ; hsa-mir-512-3p ; hsa-mir-520e ; hsa-mir-520d-3p ; hsa-mir-520c-3p ; hsa-mir-520b ; hsa-mir-520a-3p ; hsa-mir-373-3p ; hsa-mir-372-3p ; hsa-mir-302e ; hsa-mir-302d-3p ; hsa-mir-302c-3p ; hsa-mir-302b-3p ; hsa-mir-302a-3p ; hsa-mir-93-5p ; hsa-mir-526b-3p ; hsa-mir-519d-3p ; hsa-mir-20b-5p ; hsa-mir-20a-5p ; hsa-mir-17-5p ; hsa-mir-106b-5p ; hsa-mir-106a-5p ; hsa-mir-378a-5p ; hsa-mir-3653-5p

Nearest miRNA

hsa-mir-10226/Upstream/1398451; hsa-mir-1250/Downstream/566519;

Nearest TSS

Nearest CpG islands

None/Target, chr17-CpG: 26/Upstream/28085, chr17-CpG: 183/Downstream/81376

Upstream sequence

acaggtgtgaaccaccatgcccagcagcaaatactttttattttattttagagatcagatctatcatcatgccattgGCAACACCCTTGTGAATACTAGT

Downstream sequence

CCCTGCATTCTGGTAATTTAGTCCAATTTCCATGTGTCGTGCAGGTAATTGTATCATTTCCAAACATCGCATGTTGTGGCAAACATTCAAAAACTGCTGT