Basic Information
VIS ID
TVIS10018679
Fusion event
HBV-chr1 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1792
Integrated sequence
CGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCAT| |AAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTG
Host Sequence
Chromosome
chr1
Cytoband
p31.1
Reference genome
GRCh37.55
Start
74394962/73929279 (Hg38)
End
74394962/73929279 (Hg38)
Fragile sites / regions
FRA1L
Nearest miRNA
hsa-mir-101-1/Upstream/2861563; hsa-mir-11399/Downstream/3130864;
Nearest TSS
ENST00000473358/Upstream/219911; ENST00000529485/Downstream/145511;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/1645226, chr1-CpG: 24/Downstream/268863
Nearby gene
LRRIQ3
Upstream sequence
TCATGCATTTATATATGTTTATTTAAATTTCTCTAAATTTAATTTGAATAAGGCAGGCAACAGCATCTCAGGGCACAGACTCATAACTGGAGACCTTCAT
Downstream sequence
CCACAAGCTTAGCTAGCTAGATTTTCCGTGTGGCCAGGACGCCTGCTGAAACTTCCAGCAGTCCTCAGAAAAACTGATGAGATACCCTTGGGCTGAATGA
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
Curate