Basic Information
VIS ID
TVIS10018680
Fusion event
HBV-chr1 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1787
Integrated sequence
ACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTA| |GGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTT
Host Sequence
Chromosome
chr1
Cytoband
p31.1
Reference genome
GRCh37.55
Start
80901031/80435346 (Hg38)
End
80901031/80435346 (Hg38)
Fragile sites / regions
FRA1L
Nearest miRNA
hsa-mir-101-1/Upstream/3375144; hsa-mir-11399/Downstream/4698448;
Nearest TSS
ENST00000473358/Upstream/60725; ENST00000418041/Downstream/100409;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/104145, chr1-CpG: 281/Downstream/1364967
Nearby gene
LINC01781
Upstream sequence
AGACTGAACTGAGATTGGAAAGTACACCTCTTTAGGCAGCTTCCGCGTGGGACACAGGGAGGAGAAAGGTCCAAGTCTGGGGACTAGCAGGTGGGTGCAG
Downstream sequence
CAAGGTGCCCAGGGAATGAGGGTTGGCAGAGTTGGGGAGTATTTCTGATGAGATCATCTGCAGGGGCTGGATAGAGATGGGTGTGGGGCCAGGAGGAGCT
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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