VISDB Viral Integration Site DataBase

VIS ID

TVIS10018688

Fusion event

HBV-UBE2D3 integration

Validated

No

Detection method

VirusFinder

Data source

Curated

Sample type

Disease

Hepatocellular carcinoma (HCC)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HBV

Reference genome

Start

1783

Integrated sequence

GTCAACGACCGACCTTGAGGCATACTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGC| |TGTAGGCATAAATTGGTCTGCGCACCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTG

Chromosome

chr4

Cytoband

q24

Reference genome

Start

End

103730668/102809511 (Hg38)

Location type

Intron4

Target gene

miRNAs that regulate target gene

hsa-mir-155-5p ; hsa-mir-101-3p ; hsa-mir-98-5p ; hsa-let-7b-5p ; hsa-mir-877-3p ; hsa-mir-423-5p ; hsa-mir-218-5p ; hsa-mir-136-5p ; hsa-mir-6126 ; hsa-mir-6864-5p ; hsa-mir-920 ; hsa-mir-6726-5p ; hsa-mir-5591-5p ; hsa-mir-4300 ; hsa-mir-3934-3p ; hsa-mir-3670 ; hsa-mir-539-5p ; hsa-mir-493-3p ; hsa-mir-4635 ; hsa-mir-3664-3p ; hsa-mir-4433a-3p ; hsa-mir-4459 ; hsa-mir-4768-3p ; hsa-mir-4453 ; hsa-mir-4538 ; hsa-mir-6854-5p ; hsa-mir-5003-3p ; hsa-mir-6833-5p ; hsa-mir-7847-3p ; hsa-mir-3190-3p ; hsa-mir-6894-5p ; hsa-mir-765 ; hsa-mir-7154-3p ; hsa-mir-766-5p ; hsa-mir-1468-3p ; hsa-mir-548x-5p ; hsa-mir-548g-5p ; hsa-mir-548f-5p ; hsa-mir-548aj-5p ; hsa-mir-4795-5p ; hsa-mir-4657 ; hsa-mir-4491 ; hsa-mir-4519 ; hsa-mir-301b-3p ; hsa-mir-130b-3p ; hsa-mir-301a-3p ; hsa-mir-3666 ; hsa-mir-4295 ; hsa-mir-454-3p ; hsa-mir-130a-3p ; hsa-mir-19b-3p ; hsa-mir-19a-3p ; hsa-mir-152-3p ; hsa-mir-148b-3p ; hsa-mir-148a-3p ; hsa-mir-188-3p ; hsa-mir-195-3p ; hsa-mir-4733-5p ; hsa-mir-16-2-3p ; hsa-mir-577 ; hsa-mir-888-5p ; hsa-mir-376c-3p ; hsa-mir-421 ; hsa-mir-7159-5p ; hsa-mir-676-5p ; hsa-mir-505-3p ; hsa-mir-6864-3p ; hsa-mir-3672 ; hsa-mir-769-5p ; hsa-mir-4786-5p ; hsa-mir-664a-5p ; hsa-mir-4794 ; hsa-mir-7162-3p ; hsa-mir-544b ; hsa-mir-6849-3p ; hsa-mir-6771-3p ; hsa-mir-1245b-3p ; hsa-mir-1249-5p ; hsa-mir-1257 ; hsa-mir-1321 ; hsa-mir-1343-5p ; hsa-mir-30a-5p ; hsa-mir-30b-5p ; hsa-mir-30c-5p ; hsa-mir-30d-5p ; hsa-mir-30e-5p ; hsa-mir-3607-5p ; hsa-mir-3613-3p ; hsa-mir-4330 ; hsa-mir-4419a ; hsa-mir-4510 ; hsa-mir-4739 ; hsa-mir-4756-5p ; hsa-mir-4790-3p ; hsa-mir-4802-5p ; hsa-mir-551b-5p ; hsa-mir-6081 ; hsa-mir-6127 ; hsa-mir-6129 ; hsa-mir-6130 ; hsa-mir-6133 ; hsa-mir-6515-5p ; hsa-mir-6783-5p ; hsa-mir-6797-5p ; hsa-mir-6799-5p ; hsa-mir-6824-5p ; hsa-mir-939-5p ; hsa-mir-942-5p

Nearest miRNA

hsa-mir-12113/Upstream/1479097; hsa-mir-1243/Downstream/6679187;

Nearest TSS

Nearest CpG islands

None/Target, chr4-CpG: 46/Upstream/48320, chr4-CpG: 130/Downstream/16963

Upstream sequence

TCTTCGTTCACAAGGTGGTTGCCTTTCTGGTCTTCTATCAATTATTTTCCCCTCACCCTGAAGTTGTTGATCAGGTCTTCTTCCAACTCGTCTTATTCCT

Downstream sequence

AACTCATTATGTTTTTTCTTTCAAATGCAGTACAACTATGGAATATCCAAAATAGAATTAACTATATGATAAAATAAACCTACAGACCAAGTTAAAAATT