Basic Information
VIS ID
TVIS10018691
Fusion event
HBV-chr5 integration
Validated
No
Detection method
VirusFinder
Data source
Curated
Sample type
Nontumor
Disease
Hepatocellular carcinoma (HCC)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29212479
Virus Sequence
Virus name
HBV
Reference genome
NC_003977
Start
1807
Integrated sequence
CTTCAAAGACTGTTTGTTTAAAGACTGGGAGGAGTTGGGGGAGGAGATTAGGTTAAAGGTCTTTGTACTAGGAGGCTGTAGGCATAAATTGGTCTGCGCA| |CCAGCACCATGCAACTTTTTCACCTCTGCCTAATCATCTCTTGTTCATGTCCTACTGTTCAAGCCTCCAAGCTGTGCCTTGGGTGGCTTTGGGGCATGGA
Host Sequence
Chromosome
chr5
Cytoband
q21.3
Reference genome
GRCh37.55
Start
104848356/105512655 (Hg38)
End
104848356/105512655 (Hg38)
Fragile sites / regions
FRA5F
Nearest miRNA
hsa-mir-10397/Upstream/4696090; hsa-mir-103a-1/Downstream/5001174;
Nearest TSS
ENST00000502646/Upstream/119685; ENST00000513676/Downstream/1468214;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/2252806, chr5-CpG: 253/Downstream/2156774
Nearby gene
RAB9BP1
Upstream sequence
tatgtctaacaggacggaagaaatgactgtgatggccttctcagaccctgtaggaaaggcctgtacctatccagtgaaagtgtctacctagactaagagg
Downstream sequence
AACAAATAAAATTTTCAGTTGCTGATAACCCTCAGGTTTTTGGGTCAGTGCAACAGCACATGAATAATAATAACCTATAAAAAGATCTTCAGAAAACCTA
Reference
Yoo, S., et al. A pilot systematic genomic comparison of recurrence risks of hepatitis B virus-associated hepatocellular carcinoma with low- and high-degree liver fibrosis. BMC Med ,2017, 15(1): 214.
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